TB-500 · research summary

Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients.

Scientific reports · 2020. Summary drawn from the study's full text. Each statement is followed by the exact sentence it comes from. This is a research summary, not medical advice.

Study type

Cross-sectional case-control study analyzing the association of 14 environmental and demographic variables with pulmonary tuberculosis using logistic regression.
“The objective of this study was to examine the association of 14 variables with TB in respiratory patients.”

Subjects

800 respiratory patients visiting the Chest Care Centre in Kanpur, India, comprising 500 sputum-positive pulmonary TB cases and 300 controls without TB.
“Eight hundred respiratory patients were tested for sputum positive pulmonary TB; 500 had TB and 300 did not.”

Sample size

800 total subjects (500 cases and 300 controls).
“Of 800 total subjects, 500 (Cases) had TB and 300 (Control) did not have TB.”

Duration

Data collection occurred from November 2016 to March 2017.
“The subjects from the two streams were surveyed face to face from November 2016 to March 2017.”

Reported findings

A subset model identified kerosene use, kitchen ventilation, gender, and workplace as the only significant variables associated with TB incidence when using adjusted odds ratios.
“In the logistic model, only four variables kerosene uses, kitchen ventilation, gender and workplace, were found significant and adequate compared to a full model of 14 variables.”
Kerosene use showed a consistent positive association with TB incidence, with an adjusted odds ratio of 2.62.
“Uses of kerosene (AOR 2.62 (1.95, 3.54)) consistently related to incidences of TB.”
Simulation estimates indicated that a 50% reduction in kerosene use could reduce the probability of TB by 13.29% in respiratory patients.
“It was estimated that 50% reduction in kerosene uses could reduce the probability of TB by 13.29% in respiratory patients.”

Limitations stated by the authors

The study population was drawn primarily from Kanpur and nearby districts in Uttar Pradesh, India, limiting the generalizability of findings to other regions or states.
“The findings of this study, in a strict sense, may not hold true for the rest of the districts in Uttar Pradesh or other states in India.”

Source: PubMed 33318598 · DOI 10.1038/s41598-020-79023-5 · all study summaries

Reported findings

A subset model identified kerosene use, kitchen ventilation, gender, and workplace as the only significant variables associated with TB incidence when using adjusted odds ratios.

“In the logistic model, only four variables kerosene uses, kitchen ventilation, gender and workplace, were found significant and adequate compared to a full model of 14 variables.”

Kerosene use showed a consistent positive association with TB incidence, with an adjusted odds ratio of 2.62.

“Uses of kerosene (AOR 2.62 (1.95, 3.54)) consistently related to incidences of TB.”

Simulation estimates indicated that a 50% reduction in kerosene use could reduce the probability of TB by 13.29% in respiratory patients.

“It was estimated that 50% reduction in kerosene uses could reduce the probability of TB by 13.29% in respiratory patients.”

Limitations stated by the authors

The study population was drawn primarily from Kanpur and nearby districts in Uttar Pradesh, India, limiting the generalizability of findings to other regions or states.

“The findings of this study, in a strict sense, may not hold true for the rest of the districts in Uttar Pradesh or other states in India.”