Loading
Semax · research summary
Journal of clinical medicine · 2026. Summary drawn from the study's full text. Each statement is followed by the exact sentence it comes from. This is a research summary, not medical advice.
Retrospective pilot clinical study
“This retrospective pilot clinical study included ten late adolescents (mean age 16.0 ± 1.3 years; range 13.8–17.7) in advanced skeletal maturation stages (CS4–CS6) with skeletal Class III malocclusion of maxillary origin.”
10 patients
“Ten patients (five males, five females) were analyzed (mean age 16.04 ± 1.28 years; late growth phase CS4–CS6).”
12 months of total protraction
“The total protraction lasted 12 months.”
Significant increase in SNA indicating forward maxillary displacement
“A significant increase in SNA was observed (mean +6.1°, p < 0.001), indicating forward maxillary displacement.”
Improvement in Wits appraisal and SeMax line
“The Wits appraisal improved by 3.3 mm (p = 0.007), and the SeMax increased by 2.9 mm (p = 0.0013).”
Source: PubMed 42074872 · DOI 10.3390/jcm15083070 · all study summaries