BPC-157 · research summary

Fabrication and characterization of biocompatible BPC-157 based chitosan hydrogel.

3 Biotech · 2026. Summary drawn from the study's full text. Each statement is followed by the exact sentence it comes from. This is a research summary, not medical advice.

Study type

In vitro physicochemical and biological characterization of a composite hydrogel
“In this study, CH/BPC composite hydrogel was fabricated and characterized for their physicochemical properties.”

Subjects

CH/BPC composite hydrogel
“In this study, CH/BPC composite hydrogel was fabricated and characterized for their physicochemical properties.”

Duration

24 hours for release profile assessment
“Furthermore, the hydrogel demonstrated excellent encapsulation (98.9 ± 0.8%) of BPC-157, with release profile of 81.2 ± 2.9% within 24 h.”

Reported findings

The hydrogel exhibited a porous structure and successful peptide incorporation indicated by hydrogen bonding.
“Fourier-transform infrared spectroscopy (FTIR) showed the presence of hydrogen bond between BPC-157 peptide and chitosan backbone, indicating successful peptide incorporation within the hydrogel matrix.”
The hydrogel demonstrated high encapsulation efficiency and significant release of BPC-157 within 24 hours.
“Furthermore, the hydrogel demonstrated excellent encapsulation (98.9 ± 0.8%) of BPC-157, with release profile of 81.2 ± 2.9% within 24 h.”
The hydrogel showed antibacterial efficacy against E. coli and S. aureus and acceptable hemocompatibility.
“In addition, the CH/BPC hydrogel demonstrated potent antibacterial efficacy, achieving up to 45.9% (Escherichia coli) and 65.0% (Staphylococcus aureus) inhibition.”

Source: PubMed 42555375 · DOI 10.1007/s13205-026-04951-4 · all study summaries