Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.

Case report of a probable adverse drug reaction to an unverified investigational peptide

“This case illustrates how pharmacologically active substances supplied through the wellness industry may evade routine medication history.”

A woman in her mid-20s presenting with persistent nausea, vomiting, and loose stools

“A woman in her mid-20s presented with 5 days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.”

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“A woman in her mid-20s presented with 5 days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.”

Symptoms persisted for 5 days prior to admission and resolved within 1 week of admission

“Symptoms improved 2 days after admission and resolved within 1 week.”

Routine investigations failed to identify an alternative cause for the gastrointestinal symptoms

“Blood tests, urinalysis, abdominal ultrasonography and cerebral MRI identified no alternative cause.”

A Naranjo score of 7 indicated probable causality between the injections and the adverse reaction

“The Naranjo score (7) indicated probable causality.”